In this paper, we explore modeling overlapping biological processes. We discuss a probabilistic model of overlapping biological processes, gene membership in those processes, and ...
The Gibbs sampling method has been widely used for sequence analysis after it was successfully applied to the problem of identifying regulatory motif sequences upstream of genes. ...
Protein-protein interactions, which form the basis for most cellular processes, result in the formation of protein interfaces. Believing that the local shape of proteins is crucia...
Yih-En Andrew Ban, Herbert Edelsbrunner, Johannes ...
Nuclear magnetic resonance (NMR) spectroscopy allows scientists to study protein structure, dynamics and interactions in solution. A necessary first step for such applications is ...
Chris Bailey-Kellogg, Sheetal Chainraj, Gopal Pand...
In a comparative map, the number of translocations in the evolutionary history of a chromosome can be estimated solely on the basis of the conserved syntenies it contains. This est...
The distribution of the lengths of genomic segments inverte during the evolutionary divergence of two species cannot be inferred d rectly from the output of genome rearrangement al...
Adrian Maler, David Sankoff, Elisabeth R. M. Tilli...
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...