Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
Background: Array CGH (Comparative Genomic Hybridisation) is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the cohybrid...
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...