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BMCBI
2006
114views more  BMCBI 2006»
13 years 11 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BMCBI
2006
107views more  BMCBI 2006»
13 years 11 months ago
CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
Jussi Paananen, Markus Storvik, Garry Wong
BMCBI
2006
150views more  BMCBI 2006»
13 years 11 months ago
TreeDyn: towards dynamic graphics and annotations for analyses of trees
Background: Analyses of biomolecules for biodiversity, phylogeny or structure/function studies often use graphical tree representations. Many powerful tree editors are now availab...
François Chevenet, Christine Brun, Anne-Lau...
BMCBI
2006
81views more  BMCBI 2006»
13 years 11 months ago
V-MitoSNP: visualization of human mitochondrial SNPs
Li-Yeh Chuang, Cheng-Hong Yang, Yu-Huei Cheng, De-...
BMCBI
2006
153views more  BMCBI 2006»
13 years 11 months ago
Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive
Background: Recent advances in genome technologies have provided an excellent opportunity to determine the complete biological characteristics of neoplastic tissues, resulting in ...
Hiro Takahashi, Takeshi Nemoto, Teruhiko Yoshida, ...
BMCBI
2006
78views more  BMCBI 2006»
13 years 11 months ago
Subfamily logos: visualization of sequence deviations at alignment positions with high information content
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...
Eric Beitz
BMCBI
2006
97views more  BMCBI 2006»
13 years 11 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
86views more  BMCBI 2006»
13 years 11 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BMCBI
2006
87views more  BMCBI 2006»
13 years 11 months ago
XML schemas for common bioinformatic data types and their application in workflow systems
Background: Today, there is a growing need in bioinformatics to combine available software tools into chains, thus building complex applications from existing single-task tools. T...
Philipp N. Seibel, Jan Krüger, Sven Hartmeier...
BMCBI
2006
199views more  BMCBI 2006»
13 years 11 months ago
PageMan: An interactive ontology tool to generate, display, and annotate overview graphs for profiling experiments
Background: Microarray technology has become a widely accepted and standardized tool in biology. The first microarray data analysis programs were developed to support pair-wise co...
Björn Usadel, Axel Nagel, Dirk Steinhauser, Y...