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BMCBI
2006
79views more  BMCBI 2006»
13 years 11 months ago
GO-Diff: Mining functional differentiation between EST-based transcriptomes
Zuozhou Chen, Weilin Wang, Xuefeng Bruce Ling, Jan...
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang
BMCBI
2006
98views more  BMCBI 2006»
13 years 11 months ago
Ebbie: automated analysis and storage of small RNA cloning data using a dynamic web server
H. Alexander Ebhardt, Kay C. Wiese, Peter J. Unrau
BMCBI
2006
118views more  BMCBI 2006»
13 years 11 months ago
A graphical model approach to automated classification of protein subcellular location patterns in multi-cell images
Background: Knowledge of the subcellular location of a protein is critical to understanding how that protein works in a cell. This location is frequently determined by the interpr...
Shann-Ching Chen, Robert F. Murphy
BMCBI
2006
122views more  BMCBI 2006»
13 years 11 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2006
107views more  BMCBI 2006»
13 years 11 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
BMCBI
2006
137views more  BMCBI 2006»
13 years 11 months ago
INTEGRATOR: interactive graphical search of large protein interactomes over the Web
Background: The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces...
Aaron N. Chang, Jason McDermott, Zachary Frazier, ...
BMCBI
2006
159views more  BMCBI 2006»
13 years 11 months ago
EpiJen: a server for multistep T cell epitope prediction
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
Irini A. Doytchinova, Pingping Guan, Darren R. Flo...