BMCBI
2006
13 years 11 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
BMCBI
2006
13 years 11 months ago
2006
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
BMCBI
2006
13 years 11 months ago
2006
Background: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding...
BMCBI
2006
13 years 11 months ago
2006
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
BMCBI
2006
13 years 11 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
BMCBI
2006
13 years 11 months ago
2006
BMCBI
2006
13 years 11 months ago
2006
Background: Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viru...
BMCBI
2006
13 years 11 months ago
2006
BMCBI
2006
13 years 11 months ago
2006
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
BMCBI
2006
13 years 11 months ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...