Sciweavers

BMCBI
2007
102views more  BMCBI 2007»
14 years 14 days ago
A mixture of feature experts approach for protein-protein interaction prediction
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Yanjun Qi, Judith Klein-Seetharaman, Ziv Bar-Josep...
BMCBI
2007
101views more  BMCBI 2007»
14 years 14 days ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BMCBI
2007
155views more  BMCBI 2007»
14 years 14 days ago
Current approaches to gene regulatory network modelling
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network part...
Thomas Schlitt, Alvis Brazma
BMCBI
2007
113views more  BMCBI 2007»
14 years 14 days ago
Statistical tools for transgene copy number estimation based on real-time PCR
Background: As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughpu...
Joshua S. Yuan, Jason N. Burris, Nathan R. Stewart...
BMCBI
2007
133views more  BMCBI 2007»
14 years 14 days ago
An efficient pseudomedian filter for tiling microrrays
Background: Tiling microarrays are becoming an essential technology in the functional genomics toolbox. They have been applied to the tasks of novel transcript identification, elu...
Thomas E. Royce, Nicholas Carriero, Mark B. Gerste...
BMCBI
2007
147views more  BMCBI 2007»
14 years 14 days ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
BMCBI
2007
55views more  BMCBI 2007»
14 years 14 days ago
Inference of miRNA targets using evolutionary conservation and pathway analysis
Dimos Gaidatzis, Erik van Nimwegen, Jean Hausser, ...
BMCBI
2007
107views more  BMCBI 2007»
14 years 14 days ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
BMCBI
2007
109views more  BMCBI 2007»
14 years 14 days ago
Discarding duplicate ditags in LongSAGE analysis may introduce significant error
Background: During gene expression analysis by Serial Analysis of Gene Expression (SAGE), duplicate ditags are routinely removed from the data analysis, because they are suspected...
Jeppe Emmersen, Anna M. Heidenblut, Annabeth Laurs...