BMCBI
2007
14 years 14 days ago
2007
Background: Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) a...
BMCBI
2007
14 years 14 days ago
2007
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
BMCBI
2007
14 years 14 days ago
2007
Background: The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequenc...
BMCBI
2007
14 years 14 days ago
2007
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...
BMCBI
2007
14 years 14 days ago
2007
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
BMCBI
2007
14 years 14 days ago
2007
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
BMCBI
2007
14 years 14 days ago
2007
Background: There are a number of different methods for generation of trees and algorithms for phylogenetic analysis in the study of bacterial taxonomy. Genotypic information, suc...
BMCBI
2007
14 years 14 days ago
2007
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct repeat found in a wide range of bacteria and archaea. CRISPRs are beginning to...
BMCBI
2007
14 years 14 days ago
2007
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...