BMCBI
2007
13 years 7 months ago
2007
Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...
BMCBI
2007
13 years 7 months ago
2007
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
BMCBI
2007
13 years 7 months ago
2007
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...
BMCBI
2007
13 years 7 months ago
2007
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
BMCBI
2007
13 years 7 months ago
2007
Background: Transmission electron tomography is an increasingly common three-dimensional electron microscopy approach that can provide new insights into the structure of subcellul...
BMCBI
2007
13 years 7 months ago
2007
Background: With the growing abundance of microarray data, statistical methods are increasingly needed to integrate results across studies. Two common approaches for meta-analysis...
BMCBI
2007
13 years 7 months ago
2007
BMCBI
2007
13 years 7 months ago
2007
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
BMCBI
2007
13 years 7 months ago
2007
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
BMCBI
2007
13 years 7 months ago
2007
