BMCBI
2007
14 years 18 days ago
2007
Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...
BMCBI
2007
14 years 18 days ago
2007
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
BMCBI
2007
14 years 18 days ago
2007
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...
BMCBI
2007
14 years 18 days ago
2007
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
BMCBI
2007
14 years 18 days ago
2007
Background: Transmission electron tomography is an increasingly common three-dimensional electron microscopy approach that can provide new insights into the structure of subcellul...
BMCBI
2007
14 years 18 days ago
2007
Background: With the growing abundance of microarray data, statistical methods are increasingly needed to integrate results across studies. Two common approaches for meta-analysis...
BMCBI
2007
14 years 18 days ago
2007
BMCBI
2007
14 years 18 days ago
2007
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
BMCBI
2007
14 years 18 days ago
2007
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
BMCBI
2007
14 years 18 days ago
2007
