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BMCBI
2007
126views more  BMCBI 2007»
14 years 19 days ago
Reconstruction of cell population dynamics using CFSE
Background: Quantifying cell division and death is central to many studies in the biological sciences. The fluorescent dye CFSE allows the tracking of cell division in vitro and i...
Andrew Yates, Cliburn Chan, Jessica Strid, Simon M...
BMCBI
2007
135views more  BMCBI 2007»
14 years 19 days ago
RECOVIR: An application package to automatically identify some single stranded RNA viruses using capsid protein residues that un
Background: Most single stranded RNA (ssRNA) viruses mutate rapidly to generate large number of strains having highly divergent capsid sequences. Accurate strain recognition in un...
Dianhui Zhu, George E. Fox, Sugoto Chakravarty
BMCBI
2007
141views more  BMCBI 2007»
14 years 19 days ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2007
143views more  BMCBI 2007»
14 years 19 days ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2007
74views more  BMCBI 2007»
14 years 19 days ago
TAMEE: data management and analysis for tissue microarrays
Gerhard G. Thallinger, Kerstin Baumgartner, Martin...
BMCBI
2007
80views more  BMCBI 2007»
14 years 19 days ago
AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions
Background: Replication origins are considered important sites for understanding the molecular mechanisms involved in DNA replication. Many computational methods have been develop...
David S. H. Chew, Ming-Ying Leung, Kwok Pui Choi
BMCBI
2007
106views more  BMCBI 2007»
14 years 19 days ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...
BMCBI
2007
153views more  BMCBI 2007»
14 years 19 days ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...