BMCBI
2007
13 years 7 months ago
2007
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
BMCBI
2007
13 years 7 months ago
2007
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
BMCBI
2007
13 years 7 months ago
2007
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
BMCBI
2007
13 years 7 months ago
2007
Background: Helical membrane proteins (HMPs) play a crucial role in diverse cellular processes, yet it still remains extremely difficult to determine their structures by experimen...
BMCBI
2007
13 years 7 months ago
2007
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
BMCBI
2007
13 years 7 months ago
2007
BMCBI
2007
13 years 7 months ago
2007
Background: The translation start site plays an important role in the control of translation efficiency of eukaryotic mRNAs. The recognition of the start AUG codon by eukaryotic r...
BMCBI
2007
13 years 7 months ago
2007
Background: Modeling of metabolic networks includes tasks such as network assembly, network overview, calculation of metabolic fluxes and testing the robustness of the network. Re...
BMCBI
2007
13 years 7 months ago
2007
BMCBI
2007
13 years 7 months ago
2007
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...