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BMCBI
2007
103views more  BMCBI 2007»
14 years 19 days ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2007
45views more  BMCBI 2007»
14 years 19 days ago
Regulation of metabolic networks by small molecule metabolites
Alex Gutteridge, Minoru Kanehisa, Susumu Goto
BMCBI
2007
89views more  BMCBI 2007»
14 years 19 days ago
msmsEval: tandem mass spectral quality assignment for high-throughput proteomics
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
Jason W. H. Wong, Matthew J. Sullivan, Hugh M. Car...
BMCBI
2007
114views more  BMCBI 2007»
14 years 19 days ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2007
119views more  BMCBI 2007»
14 years 19 days ago
A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments
Background: Gas chromatography-mass spectrometry (GC-MS) is a robust platform for the profiling of certain classes of small molecules in biological samples. When multiple samples ...
Mark D. Robinson, David P. De Souza, Woon Wai Keen...
BMCBI
2007
88views more  BMCBI 2007»
14 years 19 days ago
TMM@: a web application for the analysis of transmembrane helix mobility
Lars Skjaerven, Inge Jonassen, Nathalie Reuter
BMCBI
2007
101views more  BMCBI 2007»
14 years 19 days ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
BMCBI
2007
140views more  BMCBI 2007»
14 years 19 days ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...