BMCBI
2007
14 years 20 days ago
2007
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
BMCBI
2007
14 years 20 days ago
2007
Background: Marine ecological genomics can be defined as the application of genomic sciences to understand the structure and function of marine ecosystems. In this field of resear...
BMCBI
2007
14 years 20 days ago
2007
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
BMCBI
2007
14 years 20 days ago
2007
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
BMCBI
2007
14 years 20 days ago
2007
BMCBI
2007
14 years 20 days ago
2007
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
BMCBI
2007
14 years 20 days ago
2007
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
BMCBI
2007
14 years 20 days ago
2007
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
BMCBI
2007
14 years 20 days ago
2007
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
BMCBI
2007
14 years 20 days ago
2007
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...