BMCBI
2008
13 years 11 months ago
2008
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
BMCBI
2008
13 years 11 months ago
2008
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
BMCBI
2008
13 years 11 months ago
2008
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
BMCBI
2008
13 years 11 months ago
2008
Background: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides...
BMCBI
2008
13 years 11 months ago
2008
Background: Alternative RNA splicing greatly increases proteome diversity and thereby contribute to species- or tissue-specific functions. The possibility to study alternative spl...
BMCBI
2008
13 years 11 months ago
2008
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
BMCBI
2008
13 years 11 months ago
2008
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
BMCBI
2008
13 years 11 months ago
2008
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...