BMCBI
2008
13 years 11 months ago
2008
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
BMCBI
2008
13 years 11 months ago
2008
Background: Each genome has a stable distribution of the combined frequency for each k-mer and its reverse complement measured in sequence fragments as short as 1000 bps across th...
BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as U...
BMCBI
2008
13 years 11 months ago
2008
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
BMCBI
2008
13 years 11 months ago
2008
Background: Bacterial promoters, which increase the efficiency of gene expression, differ from other promoters by several characteristics. This difference, not yet widely exploite...
BMCBI
2008
13 years 11 months ago
2008
Background: Mass Spectrometry coupled to Liquid Chromatography (LC-MS) is commonly used to analyze the protein content of biological samples in large scale studies. The data resul...
BMCBI
2008
13 years 11 months ago
2008
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: Real-time PCR analysis is a sensitive DNA quantification technique that has recently gained considerable attention in biotechnology, microbiology and molecular diagnos...