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JCP
2006
157views more  JCP 2006»
13 years 11 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...
IJDMB
2006
125views more  IJDMB 2006»
13 years 11 months ago
Bi-level clustering of mixed categorical and numerical biomedical data
: Biomedical data sets often have mixed categorical and numerical types, where the former represent semantic information on the objects and the latter represent experimental result...
Bill Andreopoulos, Aijun An, Xiaogang Wang
IJSI
2008
122views more  IJSI 2008»
13 years 11 months ago
Mining Gene Expression Data using Domain Knowledge
Biology is now an information-intensive science and various research areas, like molecular biology, evolutionary biology or environmental biology, heavily depend on the availabilit...
Nicolas Pasquier, Claude Pasquier, Laurent Brisson...
BMCBI
2007
123views more  BMCBI 2007»
13 years 11 months ago
Robust clustering in high dimensional data using statistical depths
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...
BMCBI
2007
171views more  BMCBI 2007»
13 years 11 months ago
Classification of microarray data using gene networks
Background: Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) a...
Franck Rapaport, Andrei Zinovyev, Marie Dutreix, E...
BMCBI
2007
144views more  BMCBI 2007»
13 years 11 months ago
Spectral estimation in unevenly sampled space of periodically expressed microarray time series data
Background: Periodogram analysis of time-series is widespread in biology. A new challenge for analyzing the microarray time series data is to identify genes that are periodically ...
Alan Wee-Chung Liew, Jun Xian, Shuanhu Wu, David K...
BMCBI
2006
115views more  BMCBI 2006»
13 years 11 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2006
173views more  BMCBI 2006»
13 years 11 months ago
Kernel-based distance metric learning for microarray data classification
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Huilin Xiong, Xue-wen Chen
BMCBI
2006
81views more  BMCBI 2006»
13 years 11 months ago
A fisheye viewer for microarray-based gene expression data
Background: Microarray has been widely used to measure the relative amounts of every mRNA transcript from the genome in a single scan. Biologists have been accustomed to reading t...
Min Wu, Cheng Thao, Xiangming Mu, Ethan V. Munson
BMCBI
2006
142views more  BMCBI 2006»
13 years 11 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins