Predicting and proper ranking of splice sites (SS) is a challenging problem in bioinformatics and machine learning communities. Proposed method of donor and acceptor SSs predictio...
Symbolic rewriting systems are gaining interest as tools for simulating biochemical dynamics. Compared to traditional methods based on differential equations, the symbolic approac...
ECOME is an interactive, graph-based model for simulating an evolving, closed consumption web. It demonstrates the fundamental behavior of a global ecosystem over evolutionary tim...
Christopher Bystroff, Sam DeLuca, Carl N. McDaniel
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following...
This study shows an effective way to explore and visualize the structure-activity relationships (SARs) of flavonoids with antioxidant activity using structure- activity maps (SAMs...
Weiguo Fan, Xin Lin, Yu-Wei Hsieh, Johnnie W. Bake...
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...