BMCBI
2006
13 years 9 months ago
2006
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
BMCBI
2006
13 years 9 months ago
2006
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
BMCBI
2006
13 years 9 months ago
2006
Background: An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types...
BMCBI
2006
13 years 9 months ago
2006
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...
BMCBI
2006
13 years 9 months ago
2006
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
BMCBI
2006
13 years 9 months ago
2006
Background: We study the adaptation of Link Grammar Parser to the biomedical sublanguage with a focus on domain terms not found in a general parser lexicon. Using two biomedical c...
BMCBI
2006
2006
Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions
13 years 9 months ago
Background: A Nanopore Detector provides a means to transduce single molecule events into observable channel current changes. Nanopore-based detection can report directly, or indi...
BMCBI
2006
13 years 9 months ago
2006
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
BMCBI
2006
13 years 9 months ago
2006
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
BMCBI
2006
13 years 9 months ago
2006
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...