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    BMCBI
    2006
    137views more  BMCBI 2006»
    A classification-based framework for predicting and analyzing gene regulatory response
    13 years 11 months ago
    A classification-based framework for predicting and analyzing gene regulatory response
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    Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
    Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
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    BMCBI
    2006
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    Cheminformatics methods for novel nanopore analysis of HIV DNA termini
    13 years 11 months ago
    Cheminformatics methods for novel nanopore analysis of HIV DNA termini
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    Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
    Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
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    BMCBI
    2006
    91views more  BMCBI 2006»
    Development of computations in bioscience and bioinformatics and its application: review of the Symposium of Computations in Bio
    13 years 11 months ago
    Development of computations in bioscience and bioinformatics and its application: review of the Symposium of Computations in Bio
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    The first symposium of computations in bioinformatics and bioscience (SCBB06) was held in Hangzhou, China on June 21
    Youping Deng, Jun Ni, Chaoyang Zhang
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    BMCBI
    2006
    102views more  BMCBI 2006»
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
    13 years 11 months ago
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
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    Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
    Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
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    BMCBI
    2006
    90views more  BMCBI 2006»
    A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
    13 years 11 months ago
    A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
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    Background: Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immun...
    Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Mural...
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    BMCBI
    2006
    123views more  BMCBI 2006»
    Permutation test for periodicity in short time series data
    13 years 11 months ago
    Permutation test for periodicity in short time series data
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    Background: Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretica...
    Andrey A. Ptitsyn, Sanjin Zvonic, Jeffrey M. Gimbl...
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    BMCBI
    2006
    161views more  BMCBI 2006»
    A novel approach to phylogenetic tree construction using stochastic optimization and clustering
    13 years 11 months ago
    A novel approach to phylogenetic tree construction using stochastic optimization and clustering
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    Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
    Ling Qin, Yixin Chen, Yi Pan, Ling Chen
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    BMCBI
    2006
    186views more  BMCBI 2006»
    Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
    13 years 11 months ago
    Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
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    Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
    Xiaoli Li, Yin-Chet Tan, See-Kiong Ng
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    BMCBI
    2006
    117views more  BMCBI 2006»
    Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comf
    13 years 11 months ago
    Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comf
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    Background: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock...
    Nan Mei, Lei Guo, Lu Zhang 0013, Leming M. Shi, Yo...
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    BMCBI
    2006
    64views more  BMCBI 2006»
    FM-test: a fuzzy-set-theory-based approach to differential gene expression data analysis
    13 years 11 months ago
    FM-test: a fuzzy-set-theory-based approach to differential gene expression data analysis
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    Lily R. Liang, Shiyong Lu, Xuena Wang, Yi Lu, Vina...
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