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BMCBI
2006
67views more  BMCBI 2006»
13 years 11 months ago
Large-scale analysis of antigenic diversity of T-cell epitopes in dengue virus
Asif M. Khan, A. T. Heiny, Kenneth X. Lee, Kellath...
BMCBI
2006
108views more  BMCBI 2006»
13 years 11 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi
BMCBI
2006
141views more  BMCBI 2006»
13 years 11 months ago
Asymptotic behaviour and optimal word size for exact and approximate word matches between random sequences
Background: The number of k-words shared between two sequences is a simple and effcient alignment-free sequence comparison method. This statistic, D2, has been used for the cluste...
Sylvain Forêt, Miriam R. Kantorovitz, Conrad...
BMCBI
2006
161views more  BMCBI 2006»
13 years 11 months ago
Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
Background: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or prote...
Alan Christoffels, Richard Bartfai, Hamsa Srinivas...
BMCBI
2006
106views more  BMCBI 2006»
13 years 11 months ago
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....
BMCBI
2006
142views more  BMCBI 2006»
13 years 11 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2006
129views more  BMCBI 2006»
13 years 11 months ago
Independent Component Analysis-motivated Approach to Classificatory Decomposition of Cortical Evoked Potentials
Background: Independent Component Analysis (ICA) proves to be useful in the analysis of neural activity, as it allows for identification of distinct sources of activity. Applied t...
Tomasz G. Smolinski, Roger Buchanan, Grzegorz M. B...
BMCBI
2006
155views more  BMCBI 2006»
13 years 11 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...