BMCBI
2006
13 years 9 months ago
2006
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
BMCBI
2006
13 years 9 months ago
2006
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
BMCBI
2006
13 years 9 months ago
2006
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
BMCBI
2006
13 years 9 months ago
2006
BMCBI
2006
13 years 9 months ago
2006
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
BMCBI
2006
13 years 9 months ago
2006
BMCBI
2006
13 years 9 months ago
2006
BMCBI
2006
13 years 9 months ago
2006
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
BMCBI
2006
13 years 9 months ago
2006
In this short article, we discuss a simple method for assessing sample size requirements in microarray experiments. Our method starts with the output from a permutation-based anal...
BMCBI
2006
13 years 9 months ago
2006
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...