BMCBI
2006
13 years 11 months ago
2006
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
BMCBI
2006
13 years 11 months ago
2006
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
BMCBI
2006
13 years 11 months ago
2006
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
BMCBI
2006
13 years 11 months ago
2006
BMCBI
2006
13 years 11 months ago
2006
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
BMCBI
2006
13 years 11 months ago
2006
BMCBI
2006
13 years 11 months ago
2006
BMCBI
2006
13 years 11 months ago
2006
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
BMCBI
2006
13 years 11 months ago
2006
In this short article, we discuss a simple method for assessing sample size requirements in microarray experiments. Our method starts with the output from a permutation-based anal...
BMCBI
2006
13 years 11 months ago
2006
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...