BMCBI
2006
13 years 11 months ago
2006
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
BMCBI
2006
13 years 11 months ago
2006
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
BMCBI
2006
13 years 11 months ago
2006
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
BMCBI
2006
13 years 11 months ago
2006
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
BMCBI
2006
13 years 11 months ago
2006
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
BMCBI
2006
13 years 11 months ago
2006
Background: Accuracy of document retrieval from MEDLINE for gene queries is crucially important for many applications in bioinformatics. We explore five information retrieval-base...
BMCBI
2006
13 years 11 months ago
2006
Background: In recent years protein structure prediction methods using local structure information have shown promising improvements. The quality of new fold predictions has risen...
BMCBI
2006
13 years 11 months ago
2006
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
BMCBI
2006
13 years 11 months ago
2006
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
BMCBI
2006
13 years 11 months ago
2006
Background: Escherichia coli is the model organism for which our knowledge of its regulatory network is the most extensive. Over the last few years, our project has been collectin...