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    BMCBI
    2006
    154views more  BMCBI 2006»
    An improved procedure for gene selection from microarray experiments using false discovery rate criterion
    13 years 11 months ago
    An improved procedure for gene selection from microarray experiments using false discovery rate criterion
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    Background: A large number of genes usually show differential expressions in a microarray experiment with two types of tissues, and the p-values of a proper statistical test are o...
    James J. Yang, Mark C. K. Yang
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    BMCBI
    2006
    97views more  BMCBI 2006»
    PDA: Pooled DNA analyzer
    13 years 11 months ago
    PDA: Pooled DNA analyzer
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    Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
    Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy...
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    BMCBI
    2006
    165views more  BMCBI 2006»
    A stable gene selection in microarray data analysis
    13 years 11 months ago
    A stable gene selection in microarray data analysis
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    Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
    Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
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    BMCBI
    2006
    166views more  BMCBI 2006»
    Extraction of phylogenetic network modules from the metabolic network
    13 years 11 months ago
    Extraction of phylogenetic network modules from the metabolic network
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    Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
    Takuji Yamada, Minoru Kanehisa, Susumu Goto
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    BMCBI
    2006
    60views more  BMCBI 2006»
    PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory
    13 years 11 months ago
    PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory
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    Yu Xue, Ao Li, Lirong Wang, Huanqing Feng, Xuebiao...
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    BMCBI
    2006
    116views more  BMCBI 2006»
    Gene annotation and network inference by phylogenetic profiling
    13 years 11 months ago
    Gene annotation and network inference by phylogenetic profiling
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    Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
    Jie Wu, Zhenjun Hu, Charles DeLisi
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    BMCBI
    2006
    85views more  BMCBI 2006»
    Identification of physicochemical selective pressure on protein encoding nucleotide sequences
    13 years 11 months ago
    Identification of physicochemical selective pressure on protein encoding nucleotide sequences
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    Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
    Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
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    BMCBI
    2006
    165views more  BMCBI 2006»
    Improved variance estimation of classification performance via reduction of bias caused by small sample size
    13 years 11 months ago
    Improved variance estimation of classification performance via reduction of bias caused by small sample size
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    Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
    Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
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    BMCBI
    2006
    216views more  BMCBI 2006»
    Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
    13 years 11 months ago
    Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
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    Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
    Haiying Wang, Huiru Zheng, David Simpson, Francisc...
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    BMCBI
    2006
    211views more  BMCBI 2006»
    Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding s
    13 years 11 months ago
    Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding s
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    Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
    Xian Wang, Ao Li, Zhaohui Jiang, Huanqing Feng
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