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    BMCBI
    2006
    130views more  BMCBI 2006»
    Identifying biological concepts from a protein-related corpus with a probabilistic topic model
    13 years 11 months ago
    Identifying biological concepts from a protein-related corpus with a probabilistic topic model
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    Background: Biomedical literature, e.g., MEDLINE, contains a wealth of knowledge regarding functions of proteins. Major recurring biological concepts within such text corpora repr...
    Bin Zheng, David C. McLean Jr, Xinghua Lu
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    BMCBI
    2006
    172views more  BMCBI 2006»
    A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
    13 years 11 months ago
    A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
    Download  www.biomedcentral.com
    Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
    Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
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    BMCBI
    2006
    85views more  BMCBI 2006»
    Recursive SVM feature selection and sample classification for mass-spectrometry and microarray data
    13 years 11 months ago
    Recursive SVM feature selection and sample classification for mass-spectrometry and microarray data
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    Xuegong Zhang, Xin Lu, Qian Shi, Xiu-qin Xu, Hon-c...
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    BMCBI
    2006
    82views more  BMCBI 2006»
    Profiling alternatively spliced mRNA isoforms for prostate cancer classification
    13 years 11 months ago
    Profiling alternatively spliced mRNA isoforms for prostate cancer classification
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    Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
    Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
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    BMCBI
    2006
    86views more  BMCBI 2006»
    Microbial identification by mass cataloging
    13 years 11 months ago
    Microbial identification by mass cataloging
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    Background: The public availability of over 180,000 bacterial 16S ribosomal RNA (rRNA) sequences has facilitated microbial identification and classification using hybridization an...
    Zhengdong Zhang, George W. Jackson, George E. Fox,...
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    BMCBI
    2006
    181views more  BMCBI 2006»
    Automatic pathway building in biological association networks
    13 years 11 months ago
    Automatic pathway building in biological association networks
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    Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary f...
    Anton Yuryev, Zufar Mulyukov, Ekaterina Kotelnikov...
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    BMCBI
    2006
    190views more  BMCBI 2006»
    SNPs3D: Candidate gene and SNP selection for association studies
    13 years 11 months ago
    SNPs3D: Candidate gene and SNP selection for association studies
    Download  moult.ibbr.umd.edu
    Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
    Peng Yue, Eugene Melamud, John Moult
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    BMCBI
    2006
    240views more  BMCBI 2006»
    Statistical analysis of real-time PCR data
    13 years 11 months ago
    Statistical analysis of real-time PCR data
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    Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
    Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...
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    BMCBI
    2006
    120views more  BMCBI 2006»
    Classification of protein quaternary structure by functional domain composition
    13 years 11 months ago
    Classification of protein quaternary structure by functional domain composition
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    Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
    Xiaojing Yu, Chuan Wang, Yixue Li
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    BMCBI
    2006
    108views more  BMCBI 2006»
    FastGroupII: A web-based bioinformatics platform for analyses of large 16S rDNA libraries
    13 years 11 months ago
    FastGroupII: A web-based bioinformatics platform for analyses of large 16S rDNA libraries
    Download  www.biomedcentral.com
    Background: High-throughput sequencing makes it possible to rapidly obtain thousands of 16S rDNA sequences from environmental samples. Bioinformatic tools for the analyses of larg...
    Yanan Yu, Mya Breitbart, Pat McNairnie, Forest Roh...
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