BMCBI
2007
14 years 20 days ago
2007
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
BMCBI
2007
14 years 20 days ago
2007
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
BMCBI
2007
14 years 20 days ago
2007
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
BMCBI
2007
14 years 20 days ago
2007
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
BMCBI
2007
14 years 20 days ago
2007
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
BMCBI
2007
14 years 20 days ago
2007
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
BMCBI
2007
14 years 20 days ago
2007
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
BMCBI
2007
14 years 20 days ago
2007
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
14 years 20 days ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
BMCBI
2007
14 years 20 days ago
2007
Background: Over the past decade, a number of tools have emerged for the examination of homology relationships among protein sequences in a structural context. Most recent softwar...