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BMCBI
2008
110views more  BMCBI 2008»
13 years 11 months ago
Finding microRNA regulatory modules in human genome using rule induction
Background: MicroRNAs (miRNAs) are a class of small non-coding RNA molecules (20
Dang Hung Tran, Kenji Satou, Tu Bao Ho
BMCBI
2008
185views more  BMCBI 2008»
13 years 11 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...
BMCBI
2008
80views more  BMCBI 2008»
13 years 11 months ago
GeneFisher-P: variations of GeneFisher as processes in Bio-jETI
Anna-Lena Lamprecht, Tiziana Margaria, Bernhard St...
BMCBI
2008
77views more  BMCBI 2008»
13 years 11 months ago
Genomic analysis of gene regulation complexity
Brandon Barker, Jim Lund
BMCBI
2008
139views more  BMCBI 2008»
13 years 11 months ago
A topological transformation in evolutionary tree search methods based on maximum likelihood combining p-ECR and neighbor joinin
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
Maozu Guo, Jian-Fu Li, Yang Liu
BMCBI
2008
153views more  BMCBI 2008»
13 years 11 months ago
Improved general regression network for protein domain boundary prediction
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
Paul D. Yoo, Abdur R. Sikder, Bing Bing Zhou, Albe...
BMCBI
2008
76views more  BMCBI 2008»
13 years 11 months ago
Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
Metabotropic glutamate receptors (mGluRs) are G protein coupled receptors that play important roles in synaptic plasticity and other neuro-physiological and pathological processes...
Naveena Yanamala, Kalyan C. Tirupula, Judith Klein...
BMCBI
2008
111views more  BMCBI 2008»
13 years 11 months ago
Distinguishing the species of biomedical named entities for term identification
Background: Term identification is the task of grounding ambiguous mentions of biomedical named entities in text to unique database identifiers. Previous work on term identificati...
Xinglong Wang, Michael Matthews
BMCBI
2008
149views more  BMCBI 2008»
13 years 11 months ago
Accelerating the annotation of sparse named entities by dynamic sentence selection
This paper presents an active learning-like framework for reducing the human effort for making named entity annotations in a corpus. In this framework, the annotation work is perf...
Yoshimasa Tsuruoka, Jun-ichi Tsujii, Sophia Anania...
BMCBI
2008
102views more  BMCBI 2008»
13 years 11 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...